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A Randomized, Double-Blind, Placebo-Controlled Proof of Concept Study to Evaluate LB1148 for Return of Gastrointestinal Function, Post-Operative Ileus and Intra-Abdominal Adhesions in Subjects Undergoing Elective Bowel Resection

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Trial Profile

A Randomized, Double-Blind, Placebo-Controlled Proof of Concept Study to Evaluate LB1148 for Return of Gastrointestinal Function, Post-Operative Ileus and Intra-Abdominal Adhesions in Subjects Undergoing Elective Bowel Resection

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 24 Jun 2024

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At a glance

  • Drugs Tranexamic acid (Primary)
  • Indications Gastrointestinal disorders; Post-surgical adhesions; Postoperative ileus
  • Focus Proof of concept; Therapeutic Use
  • Acronyms PROFILE
  • Sponsors Leading BioSciences; Palisade Bio

    • Most Recent Events

    • 17 Jun 2024 Status changed from active, no longer recruiting to completed.
    • 09 Aug 2023 According to a Palisade Bio media release, primary endpoint (Change from baseline in extent and severity of intra-abdominal adhesions among subjects treated with LB1148 or placebo) has not been met.
    • 09 Aug 2023 Topline results presented in Palisade Bio media release.

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