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A Phase IIa Clinical Trial to Evaluate the Safety and Efficacy of Osimertinib (AZD9291) in First-line Patients With EGFR Mutation-positive Locally Advanced or Metastatic Non-small Cell Lung Cancer and Concomitant EGFR T790M Mutation at Time of Diagnosis

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A Phase IIa Clinical Trial to Evaluate the Safety and Efficacy of Osimertinib (AZD9291) in First-line Patients With EGFR Mutation-positive Locally Advanced or Metastatic Non-small Cell Lung Cancer and Concomitant EGFR T790M Mutation at Time of Diagnosis

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 21 Nov 2021

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At a glance

  • Drugs Osimertinib (Primary)
  • Indications Non-small cell lung cancer
  • Focus Therapeutic Use
  • Acronyms AZENT

    • Most Recent Events

    • 08 Nov 2021 Results assessing the efficacy of osimertinib as a first-line treatment for patients with epidermal growth factor receptor mutation-positive advanced non-small-cell lung cancer and with a coexisting low allelic fraction of Thr790Met, published in the European Journal of Cancer.
    • 19 Mar 2020 Status changed from active, no longer recruiting to completed.
    • 06 Sep 2019 Planned End Date changed from 1 May 2022 to 1 Jan 2020.

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