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A Phase I Study of Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Multiple Doses of Recombinant Humanized Anti-PD-1 Monoclonal Antibody for Injection in Patients With Advanced Solid Tumors

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Trial Profile

A Phase I Study of Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Multiple Doses of Recombinant Humanized Anti-PD-1 Monoclonal Antibody for Injection in Patients With Advanced Solid Tumors

Status: Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 10 Oct 2021

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At a glance

  • Drugs Toripalimab (Primary)
  • Indications Adenocarcinoma; Alveolar soft part sarcoma; Bladder cancer; Carcinoma; Diffuse large B cell lymphoma; Head and neck cancer; Hodgkin's disease; Nasopharyngeal cancer; Non-small cell lung cancer; Soft tissue sarcoma; Solid tumours
  • Focus Adverse reactions; First in man; Therapeutic Use
  • Sponsors Shanghai Junshi Biosciences

    • Most Recent Events

    • 27 Mar 2020 Results assessing the safety and tolerability of toripalimab in Chinese patients with advanced or recurrent malignant tumor refractory to standard treatment published in the European Journal of Cancer
    • 21 Oct 2019 Planned End Date changed from 1 Dec 2019 to 1 Dec 2020.
    • 21 Oct 2019 Planned primary completion date changed from 1 Sep 2019 to 1 Sep 2020.

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