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A Multi-Center, Open Label Study to Assess the Safety, Steady-State Pharmacokinetics and Pharmacodynamics of IMG-7289 With and Without ATRA (Tretinoin) in Patients With Advanced Myeloid Malignancies

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Trial Profile

A Multi-Center, Open Label Study to Assess the Safety, Steady-State Pharmacokinetics and Pharmacodynamics of IMG-7289 With and Without ATRA (Tretinoin) in Patients With Advanced Myeloid Malignancies

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 13 Jul 2023

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At a glance

  • Drugs Bomedemstat (Primary) ; Tretinoin
  • Indications Acute myeloid leukaemia; Myelodysplastic syndromes
  • Focus Adverse reactions
  • Sponsors Imago BioSciences

    • Most Recent Events

    • 24 Feb 2019 Status changed from active, no longer recruiting to completed.
    • 21 Aug 2018 According to an Imago BioSciences media release, enrolment in this phase 1/2a trial has been completed and the phase 2a expansion cohort remains ongoing.
    • 08 Aug 2018 Planned End Date changed from 1 Jun 2018 to 1 Dec 2018.

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