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Randomized Phase II Study of Neoadjuvant Nivolumab With and Without Urelumab in Cisplatin-Ineligible or Chemotherapy-refusing Patients With Muscle-Invasive Urothelial Carcinoma of the Bladder

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Trial Profile

Randomized Phase II Study of Neoadjuvant Nivolumab With and Without Urelumab in Cisplatin-Ineligible or Chemotherapy-refusing Patients With Muscle-Invasive Urothelial Carcinoma of the Bladder

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 23 Apr 2026

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At a glance

  • Drugs Nivolumab (Primary) ; Urelumab (Primary)
  • Indications Bladder cancer
  • Focus Therapeutic Use

Most Recent Events

  • 06 Apr 2026 Planned End Date changed from 1 Dec 2026 to 1 Dec 2027.
  • 06 Apr 2026 Planned primary completion date changed from 31 Jul 2026 to 31 Jul 2027.
  • 15 Jul 2025 Planned End Date changed from 1 Dec 2025 to 1 Dec 2026.

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