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TAS-102 and Bevacizumab as third line chemotherapy for colorectal cancer. Phase 2 trial

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Trial Profile

TAS-102 and Bevacizumab as third line chemotherapy for colorectal cancer. Phase 2 trial

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 14 Jun 2021

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At a glance

  • Drugs Bevacizumab (Primary) ; Tipiracil/trifluridine (Primary)
  • Indications Adenocarcinoma; Colorectal cancer
  • Focus Therapeutic Use
  • Acronyms TAS-CC3

    • Most Recent Events

    • 01 Jun 2021 Results of post-hoc analysis assessing predictive and prognostic values of pre-treatment blood inflammation-based scores, including the neutrophil-to-lymphocyte (NLR), platelet-to-lymphocyte (PLR) and lymphocyte-to-monocyte ratio (LMR) on disease-control (DC), PFS and OS, published in the Anticancer Research.
    • 25 Jan 2020 Results of post hoc analysis assessing pretreatment lymphocyte-to-monocyte ratio (LMR) to predict treatment efficacy presented at the 2020 Gastrointestinal Cancers Symposium
    • 19 Jan 2019 Primary endpoint (Progression free survival) has been met as per the results presented at the 2019 Gastrointestinal Cancers Symposium.

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