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A Phase I/II Trial of T Cell Receptor Gene Therapy Targeting HPV-16 E7 With or Without PD-1 Blockade for HPV-Associated Cancers

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A Phase I/II Trial of T Cell Receptor Gene Therapy Targeting HPV-16 E7 With or Without PD-1 Blockade for HPV-Associated Cancers

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 18 Oct 2024

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At a glance

  • Drugs Aldesleukin (Primary) ; KITE 439 (Primary) ; Cyclophosphamide; Fludarabine
  • Indications Anal cancer; Cancer; Cervical cancer; Head and neck cancer; Oropharyngeal cancer; Penile cancer; Vulvovaginal cancer
  • Focus Adverse reactions; Therapeutic Use

    • Most Recent Events

    • 02 Dec 2022 Planned primary completion date changed from 31 Dec 2024 to 31 Dec 2025.
    • 12 Jan 2022 Planned primary completion date changed from 1 Jan 2026 to 31 Dec 2024.
    • 09 Jan 2021 Planned primary completion date changed from 31 Dec 2020 to 1 Jan 2026.

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