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Evaluation of the Safety and Efficacy of an Edoxaban-based Compared to a Vitamin K Antagonist-based Antithrombotic Regimen in Subjects With Atrial Fibrillation Following Successful Percutaneous Coronary Intervention (PCI) With Stent Placement

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Trial Profile

Evaluation of the Safety and Efficacy of an Edoxaban-based Compared to a Vitamin K Antagonist-based Antithrombotic Regimen in Subjects With Atrial Fibrillation Following Successful Percutaneous Coronary Intervention (PCI) With Stent Placement

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 01 Dec 2021

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At a glance

  • Drugs Edoxaban (Primary) ; Acenocoumarol; Aspirin; Clopidogrel; Fluindione; Phenprocoumon; Prasugrel; Ticagrelor; Warfarin
  • Indications Acute coronary syndromes; Cardiovascular disorders; Coronary artery disease; Embolism and thrombosis
  • Focus Adverse reactions
  • Acronyms ENTRUST-AF-PCI
  • Sponsors Daiichi Sankyo Europe

    • Most Recent Events

    • 01 Sep 2020 Results of pre-specified sub-analysis assessing safety and efficacy of edoxaban in combination with P2Y12 inhibition, presented at the ESC Congress 2020 - Annual Congress of the European Society of Cardiology.
    • 29 Aug 2020 Results published in the European Heart Journal
    • 01 May 2020 Results (n=6335) of meta analysis from three clinical studies: ENTRUST, PIONEER and REDUAL assessing use of dual therapy versus triple therapy in patients with atrial fibrillation and acute coronary syndrome were presented at the 72nd Annual Meeting of the American Academy of Neurology

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