Trial Profile

Phase II Study Of Combination Ruxolitinib (INCB018424) With Preoperative Chemotherapy For Triple Negative Inflammatory Breast Cancer

Status: Active, no longer recruiting

Phase of Trial: Phase II

Latest Information Update: 09 Feb 2026

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At a glance

Drugs Ruxolitinib (Primary) ; Cyclophosphamide; Doxorubicin; Paclitaxel
Indications Advanced breast cancer; Early breast cancer; HER2 negative breast cancer; Inflammatory breast cancer; Male breast cancer; Triple negative breast cancer
Focus Pharmacodynamics

Most Recent Events

04 Feb 2026 Planned End Date changed from 1 Dec 2025 to 1 Apr 2026.
19 Aug 2025 Planned End Date changed from 1 Jun 2025 to 1 Dec 2025.
03 Mar 2025 Planned End Date changed from 1 Dec 2024 to 1 Jun 2025.

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