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A Phase 1, Open-Label Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of HMPL-689 in Patients With Relapsed or Refractory Lymphoma

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Trial Profile

A Phase 1, Open-Label Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of HMPL-689 in Patients With Relapsed or Refractory Lymphoma

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 01 Jul 2025

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At a glance

  • Drugs Amdizalisib (Primary)
  • Indications Chronic lymphocytic leukaemia; Follicular lymphoma; Hodgkin's disease; Lymphoma; Mantle-cell lymphoma; Marginal zone B-cell lymphoma; Non-Hodgkin's lymphoma; Peripheral T-cell lymphoma; Waldenstrom's macroglobulinaemia
  • Focus Adverse reactions
  • Sponsors Hutchison MediPharma; HUTCHMED

Most Recent Events

  • 26 Jun 2025 Status changed from active, no longer recruiting to discontinued.
  • 27 Feb 2024 Planned End Date changed from 31 Aug 2023 to 31 Dec 2024.
  • 27 Feb 2024 Planned primary completion date changed from 1 Aug 2023 to 1 Jul 2024.

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