Phase 1 / 2 Multicenter Study of the Safety, Pharmacokinetics, and Preliminary Efficacy of APL-101 in Subjects With Non-Small Cell Lung Cancer With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors
Latest Information Update: 22 Jul 2024
At a glance
- Drugs Vebreltinib (Primary) ; Osimertinib
- Indications Glioblastoma; Non-small cell lung cancer; Solid tumours
- Focus Registrational; Therapeutic Use
- Acronyms SPARTA
- Sponsors Apollomics
- 18 Jul 2024 This trial has been completed in Finland according to European Clinical Trials Database record.
- 28 Mar 2024 According to an Apollomics media release, the Company will continue enrollment in the SPARTA cohort to increase the precision around the point estimate for ORR and provide geographic diversity for the purpose of accelerated approval of an NDA to potentially support a marketing authorization. The company expect enrollment of these incremental patients in SPARTA will continue into 2025.
- 28 Mar 2024 According to an Apollomics media release, if results from SPARTA and KUNPENG studies are positive, the Company could potentially submit an NDA in 2026 to seek accelerated approval.