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Multicenter Phase 1/2 Study of Combination Therapy w/ DNA Methyltransferase Inhibitor Decitabine & Poly ADP Ribose Polymerase Inhibitor Talazoparib for Untreated AML in Adults Unfit for Cytotoxic Chemotherapy or R/R AML

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Trial Profile

Multicenter Phase 1/2 Study of Combination Therapy w/ DNA Methyltransferase Inhibitor Decitabine & Poly ADP Ribose Polymerase Inhibitor Talazoparib for Untreated AML in Adults Unfit for Cytotoxic Chemotherapy or R/R AML

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 31 Mar 2023

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At a glance

  • Drugs Decitabine (Primary) ; Talazoparib (Primary)
  • Indications Acute myeloid leukaemia
  • Focus Adverse reactions; Therapeutic Use

    • Most Recent Events

    • 01 Mar 2023 Status changed from active, no longer recruiting to completed.
    • 28 Jan 2022 Results published in the Clinical Cancer Research
    • 25 Nov 2020 Status changed from recruiting to active, no longer recruiting.

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