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A Prospective, Open-Label, Multicenter, Phase 2 Trial to Evaluate the Safety and Efficacy of the Combination of Tirabrutinib (GS-4059) and Idelalisib With and Without Obinutuzumab in Subjects With Chronic Lymphocytic Leukemia

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A Prospective, Open-Label, Multicenter, Phase 2 Trial to Evaluate the Safety and Efficacy of the Combination of Tirabrutinib (GS-4059) and Idelalisib With and Without Obinutuzumab in Subjects With Chronic Lymphocytic Leukemia

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 24 Jan 2022

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At a glance

  • Drugs Idelalisib (Primary) ; Obinutuzumab (Primary) ; Tirabrutinib (Primary)
  • Indications Chronic lymphocytic leukaemia
  • Focus Therapeutic Use
  • Sponsors Gilead Sciences

    • Most Recent Events

    • 05 Feb 2021 Status changed from active, no longer recruiting to completed.
    • 06 Nov 2019 Results assessing Safety and Efficacy of the Combination of Tirabrutinib (ONO/GS-4059) and Idelalisib with and without Obinutuzumab in Patients with Relapsed/Refractory Chronic Lymphocytic Leukemia released at the 61st Annual Meeting and Exposition of the American Society of Hematology
    • 18 Sep 2019 Planned End Date changed from 1 Feb 2024 to 1 Jan 2021.

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