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A Phase II Evaluation of Pembrolizumab, a Humanized Antibody Against PD-1, in the Treatment of Persistent or Recurrent Hypermutated/Ultramutated Endometrial Cancer Identified by Next Generation Sequencing (NGS) and Comprehensive Genomic Profiling (CGP)

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Trial Profile

A Phase II Evaluation of Pembrolizumab, a Humanized Antibody Against PD-1, in the Treatment of Persistent or Recurrent Hypermutated/Ultramutated Endometrial Cancer Identified by Next Generation Sequencing (NGS) and Comprehensive Genomic Profiling (CGP)

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 17 Jun 2025

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At a glance

  • Drugs Pembrolizumab (Primary)
  • Indications Adenocarcinoma; Carcinoma; Endometrial cancer; Sarcoma
  • Focus Adverse reactions; Therapeutic Use

Most Recent Events

  • 11 Jun 2025 Status changed from active, no longer recruiting to completed.
  • 05 Apr 2024 Primary endpoint has been changed from 24 months 4 years.
  • 05 Apr 2024 Planned End Date changed from 1 Jun 2024 to 1 Oct 2025.

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