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Phase Ib, Open-label, Multi-center Study to Characterize the Safety, Tolerability and Pharmacodynamics (PD) of PDR001 in Combination With CJM112, EGF816, Ilaris (Canakinumab) or Mekinist (Trametinib)

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Trial Profile

Phase Ib, Open-label, Multi-center Study to Characterize the Safety, Tolerability and Pharmacodynamics (PD) of PDR001 in Combination With CJM112, EGF816, Ilaris (Canakinumab) or Mekinist (Trametinib)

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 30 Mar 2022

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At a glance

  • Drugs Spartalizumab (Primary) ; Canakinumab; CJM 112; Nazartinib; Trametinib
  • Indications Adenocarcinoma; Advanced breast cancer; Colorectal cancer; Non-small cell lung cancer; Triple negative breast cancer
  • Focus Adverse reactions
  • Sponsors Novartis Pharmaceuticals

    • Most Recent Events

    • 27 Apr 2021 Status changed from active, no longer recruiting to completed.
    • 17 Mar 2021 Planned End Date changed from 1 Mar 2021 to 18 Mar 2021.
    • 17 Mar 2021 Planned primary completion date changed from 1 Mar 2021 to 18 Mar 2021.

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