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A Randomized, Double-blind, Placebo-controlled, Phase III Multicenter Study of Subcutaneous Secukinumab in Prefilled Syringes, to Compare Efficacy at 16 Weeks With Placebo and to Assess Safety and Tolerability up to 52 Weeks in Subjects With Active Ankylosing Spondylitis

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Trial Profile

A Randomized, Double-blind, Placebo-controlled, Phase III Multicenter Study of Subcutaneous Secukinumab in Prefilled Syringes, to Compare Efficacy at 16 Weeks With Placebo and to Assess Safety and Tolerability up to 52 Weeks in Subjects With Active Ankylosing Spondylitis

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 05 Nov 2021

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At a glance

  • Drugs Secukinumab (Primary)
  • Indications Ankylosing spondylitis
  • Focus Registrational; Therapeutic Use
  • Acronyms MEASURE 5
  • Sponsors Novartis; Novartis Pharmaceuticals
  • Most Recent Events

    • 05 Jun 2021 Results of post-hoc pooled analysis of 6 studies (MEASURE 1-5 & PREVENT) presented at the 22nd Annual Congress of the European League Against Rheumatism.
    • 15 Jun 2019 Primary endpoint has been met. (The proportion of participants who achieve an ASAS 20 response (Assessment of SpondyloArthritis International Society criteria))
    • 15 Jun 2019 Results of efficacy and safety of the MEASURE 5 study presented at the 20th Annual Congress of the European League Against Rheumatism

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