A Phase III Randomized Trial for Newly Diagnosed High Risk B-Lymphoblastic Leukemia (B-ALL) Including a Stratum Evaluating Dasatinib (NSC#732517) in Patients With Ph-like Tyrosine Kinase Inhibitor (TKI) Sensitive Mutations
Latest Information Update: 01 Jun 2026
At a glance
- Drugs Dasatinib (Primary) ; Clofarabine; Cyclophosphamide; Cytarabine; Cytarabine; Cytarabine; Daunorubicin; Dexamethasone; Dexamethasone; Doxorubicin; Etoposide; Folinic acid; Folinic acid; Hydrocortisone sodium succinate; Mercaptopurine; Methotrexate; Methotrexate; Pegaspargase; Prednisone; Prednisone; Tioguanine; Vincristine
- Indications CNS cancer; Leukaemia; Precursor B-cell lymphoblastic leukaemia-lymphoma; Testicular cancer
- Focus Therapeutic Use
Most Recent Events
- 28 May 2026 Status changed from active, no longer recruiting to completed.
- 29 Oct 2025 Planned End Date changed from 3 Oct 2025 to 3 Oct 2026.
- 13 Nov 2024 Planned End Date changed from 22 Sep 2024 to 3 Oct 2025.