An Exploratory, Double-blind, Randomized, Placebo-controlled, Single-center, Two-way Cross-over Study With KH176 in Patients With the Mitochondrial DNA tRNALeu(UUR) m.3243A>G Mutation and Clinical Signs of Mitochondrial Disease
Latest Information Update: 10 Feb 2022
At a glance
- Drugs Sonlicromanol (Primary)
- Indications Leber's hereditary optic atrophy; Leigh disease; MELAS syndrome; Mitochondrial disorders
- Focus Proof of concept; Therapeutic Use
- Acronyms KHENERGY
- Sponsors Khondrion
- 31 Jul 2018 According to a Khondrion media release, the company has received a grant of EUR 2.3M from the EU Horizon 2020 SME instrument program, which will be used for the execution of this clinical trial.
- 30 Jul 2018 Results (n=20) published in the Clinical Pharmacology and Therapeutics.
- 22 Feb 2018 Status changed from recruiting to completed.