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A Phase 2, Two-Group, Two-Stage, Open-Label Study of Avelumab in Patients With MSS, MSI-H and POLE-mutated Recurrent or Persistent Endometrial Cancer, Avelumab / Talazoparib in Patients With MSS Recurrent or Persistent Endometrial Cancer, and Avelumab / Axitinib in Patients With MSS Recurrent or Persistent Endometrial Cancer

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Trial Profile

A Phase 2, Two-Group, Two-Stage, Open-Label Study of Avelumab in Patients With MSS, MSI-H and POLE-mutated Recurrent or Persistent Endometrial Cancer, Avelumab / Talazoparib in Patients With MSS Recurrent or Persistent Endometrial Cancer, and Avelumab / Axitinib in Patients With MSS Recurrent or Persistent Endometrial Cancer

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 17 Jul 2024

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At a glance

  • Drugs Avelumab (Primary) ; Axitinib; Talazoparib
  • Indications Carcinoma; Endometrial cancer
  • Focus Therapeutic Use

    • Most Recent Events

    • 05 Jul 2024 Planned End Date changed from 1 Mar 2027 to 1 Nov 2026.
    • 06 Jun 2023 Results presented at the 59th Annual Meeting of the American Society of Clinical Oncology.
    • 05 Apr 2023 Planned End Date changed from 1 Mar 2026 to 1 Mar 2027.

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