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Phase 2 Study of the Combination of Ibrutinib Plus Venetoclax in Subjects With Treatment-naïve Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Trial Profile

Phase 2 Study of the Combination of Ibrutinib Plus Venetoclax in Subjects With Treatment-naïve Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 10 Sep 2026

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At a glance

  • Drugs Ibrutinib (Primary) ; Venetoclax (Primary)
  • Indications Chronic lymphocytic leukaemia
  • Focus Registrational; Therapeutic Use
  • Acronyms CAPTIVATE
  • Sponsors Pharmacyclics

Most Recent Events

  • 29 May 2026 According to AbbVie media release, the company announced ,that the European Commission (EC) has authorized an expanded label for VENCLYXTO to include use in combination with ibrutinib, this approval is supported by data from the Phase 3 GLOW and Phase 2 CAPTIVATE trials.
  • 12 Jun 2025 Results presented in the Janssen Cilag Media Release.
  • 19 Nov 2024 According to a Johnson & Johnson media release, results from this study will be presented at the 66th American Society of Hematology (ASH) Annual Meeting in San Diego from December 7-10.

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