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A Randomized, Single-masked, Sham-control, Single Ascending Dose Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamic Activity of Intravitreal LKA651 in Patients With Macular Edema From Diabetic Macular Edema (DME), Neovascular Age-related Macular Degeneration (AMD), or Retinal Vein Occlusions (RVO)

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Trial Profile

A Randomized, Single-masked, Sham-control, Single Ascending Dose Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamic Activity of Intravitreal LKA651 in Patients With Macular Edema From Diabetic Macular Edema (DME), Neovascular Age-related Macular Degeneration (AMD), or Retinal Vein Occlusions (RVO)

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 18 Apr 2022

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At a glance

  • Drugs NOV-9 (Primary)
  • Indications Diabetic macular oedema; Retinal vein occlusion; Wet age-related macular degeneration
  • Focus Adverse reactions
  • Sponsors Novartis Pharmaceuticals
  • Most Recent Events

    • 13 Jun 2018 Status changed from recruiting to completed.
    • 12 Dec 2017 Planned End Date changed from 1 Jan 2018 to 6 Feb 2018.
    • 12 Dec 2017 Planned primary completion date changed from 1 Jan 2018 to 6 Feb 2018.

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