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A Phase II Clinical Trial Platform of Sensitization Utilizing Total Neoadjuvant Therapy (TNT) in Rectal Cancer

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A Phase II Clinical Trial Platform of Sensitization Utilizing Total Neoadjuvant Therapy (TNT) in Rectal Cancer

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 16 Oct 2023

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At a glance

  • Drugs Pembrolizumab (Primary) ; Veliparib (Primary) ; Capecitabine; Fluorouracil; Folinic acid; Oxaliplatin
  • Indications Adenocarcinoma; Rectal cancer
  • Focus Therapeutic Use

    • Most Recent Events

    • 21 Sep 2023 Status changed from active, no longer recruiting to completed.
    • 12 Jul 2023 Results assessing the ability of MR-based imaging to predict pathologic complete response (pCR) and correlate MR-TRG with the pathologic neoadjuvant response score, published in the Journal of Clinical Oncology.
    • 07 Jun 2023 Planned End Date changed from 21 Mar 2023 to 21 Mar 2024.

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