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A Safety and Pharmacokinetics Study of Niraparib Plus Androgen Receptor-Targeted Therapy (Apalutamide or Abiraterone Acetate Plus Prednisone) in Men With Metastatic Castration-Resistant Prostate Cancer

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Trial Profile

A Safety and Pharmacokinetics Study of Niraparib Plus Androgen Receptor-Targeted Therapy (Apalutamide or Abiraterone Acetate Plus Prednisone) in Men With Metastatic Castration-Resistant Prostate Cancer

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 08 Oct 2021

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At a glance

  • Drugs Abiraterone acetate (Primary) ; Apalutamide (Primary) ; Niraparib (Primary) ; Prednisone (Primary)
  • Indications Prostate cancer
  • Focus Adverse reactions
  • Acronyms BEDIVERE
  • Sponsors Janssen Research & Development

    • Most Recent Events

    • 15 Feb 2020 Results evaluating safety and PK of niraparib plus androgen receptor-targeted therapy (ART) in patients with metastatic castration-resistant prostate cancer, presented at the 2020 Genitourinary Cancers Symposium
    • 03 Feb 2020 According to a Janssen media release, data from this trial will be presented at the American Society of Clinical Oncology Genitourinary (ASCO GU) Cancers Symposium, taking place February 13-15 in San Francisco.
    • 26 Jul 2019 Status changed from active, no longer recruiting to completed.

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