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Risk-based, Response-adapted, Phase II Open-label Trial of Nivolumab + Brentuximab Vedotin (N + Bv) for Children, Adolescents, and Young Adults With Relapsed/Refractory (R/R) CD30 + Classic Hodgkin Lymphoma (cHL) After Failure of First-line Therapy, Followed by Brentuximab + Bendamustine (Bv + B) for Participants With a Suboptimal Response (CheckMate 744: CHECKpoint Pathway and Nivolumab Clinical Trial Evaluation)

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Risk-based, Response-adapted, Phase II Open-label Trial of Nivolumab + Brentuximab Vedotin (N + Bv) for Children, Adolescents, and Young Adults With Relapsed/Refractory (R/R) CD30 + Classic Hodgkin Lymphoma (cHL) After Failure of First-line Therapy, Followed by Brentuximab + Bendamustine (Bv + B) for Participants With a Suboptimal Response (CheckMate 744: CHECKpoint Pathway and Nivolumab Clinical Trial Evaluation)

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 17 Jul 2024

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At a glance

  • Drugs Bendamustine (Primary) ; Brentuximab vedotin (Primary) ; Nivolumab (Primary)
  • Indications Hodgkin's disease
  • Focus Therapeutic Use
  • Acronyms CheckMate 744
  • Sponsors Bristol-Myers Squibb

    • Most Recent Events

    • 11 Jul 2024 This trial has been completed in Ireland, according to European Clinical Trials Database record.
    • 05 Jul 2024 Status changed from active, no longer recruiting to completed.
    • 21 Jun 2024 This trial has been completed in Germany (Global end date: 28 May 2024).

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