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A Randomized, Double-blind, Multicenter Study to Assess the Safety and Efficacy of a 6 Month Oral Treatment With the Chymase Inhibitor BAY 1142524 at a Dose of 25 mg BID in Comparison to Placebo on Top of Standard of Care in Patients With Reduced Left-ventricular Ejection Fraction (LVEF≤ 45%) After Acute Myocardial Infarction

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Trial Profile

A Randomized, Double-blind, Multicenter Study to Assess the Safety and Efficacy of a 6 Month Oral Treatment With the Chymase Inhibitor BAY 1142524 at a Dose of 25 mg BID in Comparison to Placebo on Top of Standard of Care in Patients With Reduced Left-ventricular Ejection Fraction (LVEF≤ 45%) After Acute Myocardial Infarction

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 05 Nov 2021

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At a glance

  • Drugs Fulacimstat (Primary)
  • Indications Left ventricular dysfunction
  • Focus Registrational; Therapeutic Use
  • Acronyms CHIARA MIA 2
  • Sponsors Bayer

    • Most Recent Events

    • 11 Sep 2018 Status changed from active, no longer recruiting to completed.
    • 01 Aug 2018 Trial has been completed in Czech Republic.
    • 15 Mar 2018 Planned End Date changed from 21 Sep 2018 to 5 Sep 2018.
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