A Randomized, Double-blind, Multicenter Study to Assess the Safety and Efficacy of a 6 Month Oral Treatment With the Chymase Inhibitor BAY 1142524 at a Dose of 25 mg BID in Comparison to Placebo on Top of Standard of Care in Patients With Reduced Left-ventricular Ejection Fraction (LVEF≤ 45%) After Acute Myocardial Infarction

Trial Profile

A Randomized, Double-blind, Multicenter Study to Assess the Safety and Efficacy of a 6 Month Oral Treatment With the Chymase Inhibitor BAY 1142524 at a Dose of 25 mg BID in Comparison to Placebo on Top of Standard of Care in Patients With Reduced Left-ventricular Ejection Fraction (LVEF≤ 45%) After Acute Myocardial Infarction

Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 20 Apr 2018

At a glance

  • Drugs Fulacimstat (Primary)
  • Indications Left ventricular dysfunction
  • Focus Therapeutic Use
  • Acronyms CHIARA MIA 2
  • Sponsors Bayer
  • Most Recent Events

    • 15 Mar 2018 Planned End Date changed from 21 Sep 2018 to 5 Sep 2018.
    • 15 Mar 2018 Planned primary completion date changed from 17 Aug 2018 to 1 Aug 2018.
    • 13 Feb 2018 Status changed from recruiting to active, no longer recruiting.
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