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A Multicentre, Randomized, Double-blinded, Placebo-controlled, Parallel Group, Single-dose Design to Determine the Efficacy and Safety of Intravenous NA-1 in Subjects With Acute Ischemic Stroke Undergoing Endovascular Thrombectomy

Trial Profile

A Multicentre, Randomized, Double-blinded, Placebo-controlled, Parallel Group, Single-dose Design to Determine the Efficacy and Safety of Intravenous NA-1 in Subjects With Acute Ischemic Stroke Undergoing Endovascular Thrombectomy

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 03 Oct 2023

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At a glance

  • Drugs Nerinetide (Primary)
  • Indications Stroke
  • Focus Registrational; Therapeutic Use
  • Acronyms ESCAPE-NA1
  • Sponsors NoNO
  • Most Recent Events

    • 23 Jan 2024 Results (n=77) of analysis assessing infarct evolution on MR-DWI after thrombectomy in patients included had MRI of sufficient quality published in the Neurology
    • 01 Sep 2023 Results assessing whether CTP modifies the effect of near-complete reperfusion on clinical outcomes, ie, whether poor clinical outcomes despite near-complete reperfusion can be partly or fully explained by CTP findings published in the American Journal of Neuroradiology
    • 12 Apr 2023 Results (n=1092) assessing the incidence of Infarct in a new territory, outcomes after Infarct in a new territory, and the impact of concurrent treatments with intravenous thrombolysis and nerinetide, published in the Stroke.
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