Trial Profile

An Adaptive Phase I/II Study to Assess Safety, Efficacy, Pharmacokinetics and Pharmacodynamics of Crovalimab in Healthy Volunteers and Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH)

Status: Completed

Phase of Trial: Phase I/II

Latest Information Update: 04 Sep 2026

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At a glance

Drugs Crovalimab (Primary) ; Crovalimab (Primary)
Indications Paroxysmal nocturnal haemoglobinuria
Focus Adverse reactions; First in man; Pharmacodynamics; Pharmacokinetics
Acronyms COMPOSER
Sponsors Chugai Pharmaceutical; Roche

Most Recent Events

01 Sep 2026 Status changed from active, no longer recruiting to completed.
05 Aug 2026 Planned End Date changed from 30 Sep 2026 to 13 Aug 2026.
05 Aug 2026 Planned primary completion date changed from 30 Sep 2026 to 13 Aug 2026.

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