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A Randomised, Double-blind, Placebo-controlled, Phase 2 Study of the Efficacy and Safety of Pirfenidone in Patients With Heart Failure and Preserved Left Ventricular Ejection Fraction (PIROUETTE)

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Trial Profile

A Randomised, Double-blind, Placebo-controlled, Phase 2 Study of the Efficacy and Safety of Pirfenidone in Patients With Heart Failure and Preserved Left Ventricular Ejection Fraction (PIROUETTE)

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 04 Aug 2023

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At a glance

  • Drugs Pirfenidone (Primary)
  • Indications Heart failure
  • Focus Therapeutic Use
  • Acronyms PIROUETTE

    • Most Recent Events

    • 01 Jul 2023 Results assessing treatment adherence through pill counts and diary cards, published in the Journal of Cardiac Failure.
    • 01 Aug 2021 Primary endpoint has been met. (Extracellular volume fraction (ECV), as per Results published in the Nature Medicine
    • 01 Aug 2021 Results published in the Nature Medicine

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