Either you have JavaScript disabled or your browser does not support Javascript . To work properly, this page requires JavaScript to be enabled.
How to enable JavaScript in your browser?

A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety and Efficacy of Selonsertib in Subjects With Nonalcoholic Steatohepatitis (NASH) and Bridging (F3) Fibrosis

X
Trial Profile

A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety and Efficacy of Selonsertib in Subjects With Nonalcoholic Steatohepatitis (NASH) and Bridging (F3) Fibrosis

Status: Discontinued
Phase of Trial: Phase III

Latest Information Update: 07 Aug 2023

Price : $35 *
  • Adis is an information provider.
  • Final gross price and currency may vary according to local VAT and billing address.
  • Your purchase entitles you to full access to the information contained in our trial profile at the time of purchase.
  • A link to download a PDF version of the trial profile will be included in your email receipt.

At a glance

  • Drugs Selonsertib (Primary)
  • Indications Hepatic fibrosis; Liver cirrhosis; Non-alcoholic steatohepatitis
  • Focus Registrational; Therapeutic Use
  • Acronyms STELLAR-3
  • Sponsors Gilead Sciences
  • Most Recent Events

    • 24 Jun 2023 Results assessing the associations between use ofantidiabetic or lipid-lowering drugs and blood liver fibrosis biomarkers from two phase III trials of NASH patients with bridging fibrosis (NCT03053050, N=785) or compensated cirrhosis(NCT03053063, N=864), presented at the European Association for the Study of the Liver Congress 2023.
    • 26 Jun 2022 Results of a pooled analysis of data from STELLAR 3 and STELLAR 4 studies of liver biopsy images, and used it to identify baseline gene signatures that are predictive of fibrosis progression or regression in NASH with the help of machine learning, presented at The International Liver Congress 2022
    • 26 Jun 2022 Results from NCT03053050 and NCT03053063 studies assessing the prognostic utility of machine learning-facilitated continuous scoring of histologic features presented at The International Liver Congress 2022

You need to be a logged in or subscribed to view this content Request demo

If your organization or you do not have a subscription, try one of the following:
  • Contacting your organization’s admin about adding this content to your AdisInsight subscription
  • Buying a PDF version of any individual profile
  • Request a free trial
If your organization has a subscription, there are several access options, even while working remotely:
  • Working within your organization’s network
  • with username/password or try to via your institution
  • Persisted access using your organization’s identifier stored in your user browser for 90 days
Back to top