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A Phase 3, Multicenter, Observational Long-term Study Evaluating the Safety, Tolerability, and Efficacy of Treatment of SM04690 or Placebo Previously Injected in the Target Knee Joint of Subjects With Moderately to Severely Symptomatic Osteoarthritis

Trial Profile

A Phase 3, Multicenter, Observational Long-term Study Evaluating the Safety, Tolerability, and Efficacy of Treatment of SM04690 or Placebo Previously Injected in the Target Knee Joint of Subjects With Moderately to Severely Symptomatic Osteoarthritis

Status: Discontinued
Phase of Trial: Phase III

Latest Information Update: 10 Jan 2022

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At a glance

  • Drugs Lorecivivint (Primary)
  • Indications Osteoarthritis
  • Focus Adverse reactions
  • Sponsors Biosplice Therapeutics; Samumed

Most Recent Events

  • 09 Nov 2021 Status has been changed to discontinued, according results presented at the ACR Convergence 2021.
  • 28 Aug 2021 Results presented at the 2021 World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases
  • 05 Jun 2021 Results of post-hoc efficacy analysis from three clinical studies: NCT02951026, NCT02536833 and NCT03122860 presented at the 22nd Annual Congress of the European League Against Rheumatism

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