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A Phase 3, Multicenter, Observational Long-term Study Evaluating the Safety, Tolerability, and Efficacy of Treatment of SM04690 or Placebo Previously Injected in the Target Knee Joint of Subjects With Moderately to Severely Symptomatic Osteoarthritis

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Trial Profile

A Phase 3, Multicenter, Observational Long-term Study Evaluating the Safety, Tolerability, and Efficacy of Treatment of SM04690 or Placebo Previously Injected in the Target Knee Joint of Subjects With Moderately to Severely Symptomatic Osteoarthritis

Status: Discontinued
Phase of Trial: Phase III

Latest Information Update: 10 Jan 2022

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At a glance

  • Drugs Lorecivivint (Primary)
  • Indications Osteoarthritis
  • Focus Adverse reactions
  • Sponsors Biosplice Therapeutics; Samumed
  • Most Recent Events

    • 09 Nov 2021 Status has been changed to discontinued, according results presented at the ACR Convergence 2021.
    • 28 Aug 2021 Results presented at the 2021 World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases
    • 05 Jun 2021 Results of post-hoc efficacy analysis from three clinical studies: NCT02951026, NCT02536833 and NCT03122860 presented at the 22nd Annual Congress of the European League Against Rheumatism

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