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A Phase 1b, Dose Escalation Study to Determine the Recommended Phase 2 Dose of TAK-659 in Combination With Bendamustine (±Rituximab), Gemcitabine, Lenalidomide, or Ibrutinib for the Treatment of Patients With Advanced Non-Hodgkin Lymphoma After At Least 1 Prior Line of Therapy

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Trial Profile

A Phase 1b, Dose Escalation Study to Determine the Recommended Phase 2 Dose of TAK-659 in Combination With Bendamustine (±Rituximab), Gemcitabine, Lenalidomide, or Ibrutinib for the Treatment of Patients With Advanced Non-Hodgkin Lymphoma After At Least 1 Prior Line of Therapy

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 21 Feb 2022

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At a glance

  • Drugs Bendamustine (Primary) ; Gemcitabine (Primary) ; Ibrutinib (Primary) ; Lenalidomide (Primary) ; Mivavotinib (Primary) ; Rituximab (Primary)
  • Indications Diffuse large B cell lymphoma; Follicular lymphoma; Marginal zone B-cell lymphoma; Non-Hodgkin's lymphoma
  • Focus Adverse reactions; Pharmacokinetics
  • Sponsors Takeda Oncology
  • Most Recent Events

    • 07 Dec 2021 Status changed from completed to discontinued.
    • 10 Aug 2020 Status changed from active, no longer recruiting to completed.
    • 10 Jul 2020 Planned End Date changed from 8 Jul 2020 to 27 Jul 2020.

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