A Randomised, Double-Blind, Placebo-Controlled, First-Time-in-Human Study to Determine the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Multiple Ascending Doses of MT-4129 in Healthy Subjects; Including the Effect of Gender and Age on the Pharmacokinetics of a Single Dose of MT-4129 in Healthy Subjects
Latest Information Update: 20 Jan 2025
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At a glance
- Drugs Lorundrostat (Primary)
- Indications Cardiovascular disorders; Hypertension
- Focus Adverse reactions; First in man
- Sponsors Mitsubishi Tanabe Pharma Corporation
- 06 Mar 2023 Results of a first-in-human trial of MLS-101, a novel small molecule inhibitor with CYP11B2 selectivity presented at the 72nd Annual Scientific Session of the American College of Cardiology together with the World Heart Federation
- 20 Feb 2023 According to a Mineralys Therapeutics media release, data from this study will be presented at the American College of Cardiologys 72nd Annual Scientific Session together with the World Congress of Cardiology (ACC.23/WCC).
- 08 Apr 2021 Results published in the Mitsubishi Tanabe Pharma Corporation media release.