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ENSIGN: Phase II Window of Opportunity Trial of Stereotactic Body Radiation Therapy and In Situ Gene Therapy Followed by Nivolumab in Metastatic Squamous or Non-Squamous Non-Small Cell Lung Carcinoma and Metastatic Uveal Melanoma

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Trial Profile

ENSIGN: Phase II Window of Opportunity Trial of Stereotactic Body Radiation Therapy and In Situ Gene Therapy Followed by Nivolumab in Metastatic Squamous or Non-Squamous Non-Small Cell Lung Carcinoma and Metastatic Uveal Melanoma

Status: Discontinued
Phase of Trial: Phase II

Latest Information Update: 25 Sep 2023

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At a glance

  • Drugs Aglatimagene besadenovec (Primary) ; Nivolumab (Primary) ; Valaciclovir (Primary)
  • Indications Non-small cell lung cancer; Uveal melanoma
  • Focus Therapeutic Use
  • Acronyms ENSIGN

    • Most Recent Events

    • 17 Nov 2020 Status changed from recruiting to discontinued.
    • 08 Mar 2018 Planned number of patients changed from 29 to 25.
    • 05 Apr 2017 Trial design presented at the 108th Annual Meeting of the American Association for Cancer Research

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