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A Phase I/II Basket Trial of the EGF Vaccine CIMAvax in Combination With Anti-PD1 Therapy in Patients With Advanced NSCLC or Squamous Head and Neck Cancer

Trial Profile

A Phase I/II Basket Trial of the EGF Vaccine CIMAvax in Combination With Anti-PD1 Therapy in Patients With Advanced NSCLC or Squamous Head and Neck Cancer

Status: Suspended
Phase of Trial: Phase I/II

Latest Information Update: 04 Mar 2025

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At a glance

  • Drugs BV NSCLC 001 (Primary) ; Nivolumab (Primary) ; Pembrolizumab (Primary)
  • Indications Adenocarcinoma; Head and neck cancer; Non-small cell lung cancer; Squamous cell cancer
  • Focus Adverse reactions; Therapeutic Use

Most Recent Events

  • 28 Feb 2025 Status changed from recruiting to suspended due to interim analysis
  • 06 Nov 2023 Planned number of patients changed from 193 to 242.
  • 06 Nov 2023 Planned End Date changed from 9 Dec 2023 to 9 Dec 2027.

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