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A PHASE 1 DOSE ESCALATION STUDY TO EVALUATE THE SAFETY, PHARMACOKINETICS AND PHARMACODYNAMICS OF INTRAVENOUS PF-06747143, ADMINISTERED AS SINGLE AGENT OR IN COMBINATION WITH STANDARD CHEMOTHERAPY IN ADULT PATIENTS WITH ACUTE MYELOID LEUKEMIA

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Trial Profile

A PHASE 1 DOSE ESCALATION STUDY TO EVALUATE THE SAFETY, PHARMACOKINETICS AND PHARMACODYNAMICS OF INTRAVENOUS PF-06747143, ADMINISTERED AS SINGLE AGENT OR IN COMBINATION WITH STANDARD CHEMOTHERAPY IN ADULT PATIENTS WITH ACUTE MYELOID LEUKEMIA

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 05 Nov 2021

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At a glance

  • Drugs PF 6747143 (Primary) ; Azacitidine; Azacitidine; Cytarabine; Daunorubicin; Decitabine
  • Indications Acute myeloid leukaemia
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors Pfizer

    • Most Recent Events

    • 28 Nov 2017 Status changed from recruiting to discontinued.
    • 28 Sep 2017 Planned End Date changed from 11 Feb 2020 to 1 May 2020.
    • 28 Sep 2017 Planned primary completion date changed from 11 Feb 2020 to 1 May 2020.

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