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A Phase 1b Open-Label Study Investigating the Safety and Pharmacokinetics of Administration of Subcutaneous Blinatumomab for the Treatment of Relapsed/Refractory Indolent Non-Hodgkin's Lymphoma

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Trial Profile

A Phase 1b Open-Label Study Investigating the Safety and Pharmacokinetics of Administration of Subcutaneous Blinatumomab for the Treatment of Relapsed/Refractory Indolent Non-Hodgkin's Lymphoma

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 07 Feb 2024

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At a glance

  • Drugs Blinatumomab (Primary) ; Blinatumomab (Primary)
  • Indications B-cell lymphoma; Chronic lymphocytic leukaemia; Follicular lymphoma; Mantle-cell lymphoma; Marginal zone B-cell lymphoma; Non-Hodgkin's lymphoma; Waldenstrom's macroglobulinaemia
  • Focus Adverse reactions
  • Sponsors Amgen

    • Most Recent Events

    • 18 Mar 2022 Results of pharmacokinetic pharmacodynamic modeling of subcutaneous blinatumomab by using data from Phase 1 I-NHL and R/R ALL monotherapy studies presented at the 123rd Annual Meeting of the American Society for Clinical Pharmacology and Therapeutics
    • 14 Dec 2021 Results evaluatingsubcutaneous (SC) blinatumomab, which may simplify administration, improve convenience, and potentially reduce adverse events (AEs) presented at the 63rd American Society of Hematology Annual Meeting and Exposition
    • 08 Sep 2021 Status changed from active, no longer recruiting to completed.

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