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A randomized, double-blind, placebo-controlled multicenter phase 2 dose-ranging study to assess the safety and efficacy of multiple ianalumab doses administered subcutaneously in patients with moderate to severe primary Sjogren's Syndrome

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Trial Profile

A randomized, double-blind, placebo-controlled multicenter phase 2 dose-ranging study to assess the safety and efficacy of multiple ianalumab doses administered subcutaneously in patients with moderate to severe primary Sjogren's Syndrome

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 22 Jul 2024

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At a glance

  • Drugs Ianalumab (Primary)
  • Indications Sjogren's syndrome
  • Focus Therapeutic Use
  • Sponsors Novartis; Novartis Pharma KK; Novartis Pharmaceuticals
  • Most Recent Events

    • 15 Jun 2024 Results (n=190) characterizing the biomarkers associated with disease activity and clinical dose response in improving the whole salivary flow, presented at the 25th Annual Congress of the European League Against Rheumatism
    • 15 Nov 2023 Results assessing dose dependent modulation of a B cell protein signature by Ianalumab in patients with Sjogren's-syndrome presented at the ACR Convergence 2023
    • 03 Dec 2021 Results published in the Lancet.

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