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A Multicenter, Phase 2B, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Dose-Ranging Study to Evaluate the Efficacy and Safety of Bimekizumab in Subjects With Active Ankylosing Spondylitis

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Trial Profile

A Multicenter, Phase 2B, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Dose-Ranging Study to Evaluate the Efficacy and Safety of Bimekizumab in Subjects With Active Ankylosing Spondylitis

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 23 Jul 2024

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At a glance

  • Drugs Bimekizumab (Primary)
  • Indications Ankylosing spondylitis
  • Focus Therapeutic Use
  • Acronyms BE AGILE; BE-AGILE
  • Sponsors UCB Biopharma

    • Most Recent Events

    • 15 Jun 2024 Results reporting 5-year long-term safety and efficacy data from this trial and its OLE presented at the 25th Annual Congress of the European League Against Rheumatism
    • 15 Nov 2023 5-yr results of Bimekizumab in BE AGILE and its OLE, presented at the ACR Convergence 2023
    • 15 Nov 2023 Results of pooled analysis of studies (BE MOBILE 1, BE MOBILE 2, BE MOVING,BE MOBILE 1,BE MOBILE 2,BE AGILE, BE AGILE 2, assessing incidence of uveitis following inhibition of IL-7A in addition to IL-7F with bimekizumab in patients with Axial Spondyloarthritis were presented at the ACR Convergence 2023.

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