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A Phase III, Open-Label, Multicenter, Two Arm, Randomized Study to Investigate the Efficacy and Safety of Cobimetinib Plus Atezolizumab Versus Pembrolizumab in Patients With Previously Untreated Advanced BRAF V600 Wild-Type Melanoma

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Trial Profile

A Phase III, Open-Label, Multicenter, Two Arm, Randomized Study to Investigate the Efficacy and Safety of Cobimetinib Plus Atezolizumab Versus Pembrolizumab in Patients With Previously Untreated Advanced BRAF V600 Wild-Type Melanoma

Status: Discontinued
Phase of Trial: Phase III

Latest Information Update: 23 Sep 2022

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At a glance

  • Drugs Atezolizumab (Primary) ; Cobimetinib (Primary) ; Pembrolizumab
  • Indications Malignant melanoma
  • Focus Registrational; Therapeutic Use
  • Acronyms IMspire170
  • Sponsors Genentech; Roche
  • Most Recent Events

    • 24 Aug 2022 Status changed from completed to discontinued due to benefit/risk analysis.
    • 02 Jun 2021 Status changed from active, no longer recruiting to completed.
    • 09 Apr 2021 This trial has been completed in Poland (Global End Date: 19 Feb 2021), according to European Clinical Trials Database record.

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