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A Multi-center, Randomized, Double-blind, Phase II Clinical Trial to Evaluate the Efficacy and Safety of Combination Therapy vs. Monotherapy of Candesartan and Amlodipine for Dose-Finding in Patients With Essential Hypertension

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Trial Profile

A Multi-center, Randomized, Double-blind, Phase II Clinical Trial to Evaluate the Efficacy and Safety of Combination Therapy vs. Monotherapy of Candesartan and Amlodipine for Dose-Finding in Patients With Essential Hypertension

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 16 Jan 2020

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At a glance

  • Drugs Amlodipine/candesartan-cilexetil (Primary) ; Amlodipine; Candesartan cilexetil
  • Indications Essential hypertension
  • Focus Therapeutic Use
  • Sponsors Shin Poong Pharmaceutical

    • Most Recent Events

    • 19 Jul 2017 Primary endpoint (Change in mean sitting Diastolic Blood Pressure (msDBP) at week 8 compared to baseline-CAN/AML (8 mg/10 mg) versus CAN (8 mg) monotherapy) has been met, according to results published in the Clinical Therapeutics Journal.
    • 19 Jul 2017 Primary endpoint (Change in mean sitting Diastolic Blood Pressure (msDBP) at week 8 compared to baseline-CAN/AML (8 mg/5 mg, 16 mg/5 mg, and 16 mg/10 mg) versus CAN (8 mg, 16 mg) or AML (5 mg, 10 mg) monotherapy) has been met, according to results published in the Clinical Therapeutics Journal.
    • 19 Jul 2017 Results published in the Clinical Therapeutics Journal.

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