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A Phase 1, Randomized, Double Blind, Placebo Controlled, Dose Escalation, and Bioavailability Study Evaluating the Safety and Pharmacokinetics of VX-659 in Healthy Subjects and in Subjects With Cystic Fibrosis

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Trial Profile

A Phase 1, Randomized, Double Blind, Placebo Controlled, Dose Escalation, and Bioavailability Study Evaluating the Safety and Pharmacokinetics of VX-659 in Healthy Subjects and in Subjects With Cystic Fibrosis

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 05 Nov 2021

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At a glance

  • Drugs Bamocaftor (Primary) ; Ivacaftor; Tezacaftor
  • Indications Cystic fibrosis
  • Focus Adverse reactions
  • Sponsors Vertex Pharmaceuticals
  • Most Recent Events

    • 18 Oct 2018 Results from NCT03224351 and NCT03029455 studies, published in the New England Journal of Medicine.
    • 01 Sep 2017 Status changed from recruiting to completed.
    • 22 Jul 2017 There is a discrepancy in phase of the study. Accordinf to NCT it is phase 1 where as MR and conmpany website states it as phase 2. Presently retained phase as per NCT (phase 1), please update the same on receiving further information.
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