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A Phase I, Randomized, Double-Blind, Placebo-Controlled, Single and Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AMG 986 in Healthy Subjects and Heart Failure Patients

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Trial Profile

A Phase I, Randomized, Double-Blind, Placebo-Controlled, Single and Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AMG 986 in Healthy Subjects and Heart Failure Patients

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 11 Aug 2022

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At a glance

  • Drugs Azelaprag (Primary) ; Azelaprag (Primary)
  • Indications Heart failure
  • Focus Adverse reactions
  • Sponsors Amgen

Most Recent Events

  • 06 May 2019 Status changed from recruiting to discontinued.
  • 19 Oct 2018 Planned End Date changed from 21 Dec 2018 to 30 Jul 2019.
  • 19 Oct 2018 Planned primary completion date changed from 21 Dec 2018 to 30 Jul 2019.

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