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Open Label, Multi-center, Prospective Study to Investigate the Efficacy and Safety of AZD9291 in Brain Metastases From Patients With EGFR T790M Positive NSCLC Who Have Received Prior Therapy With an EGFR-TKI

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Trial Profile

Open Label, Multi-center, Prospective Study to Investigate the Efficacy and Safety of AZD9291 in Brain Metastases From Patients With EGFR T790M Positive NSCLC Who Have Received Prior Therapy With an EGFR-TKI

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 17 Sep 2021

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At a glance

  • Drugs Osimertinib (Primary)
  • Indications Adenocarcinoma; Brain metastases; Meningeal carcinomatosis; Non-small cell lung cancer
  • Focus Therapeutic Use
  • Acronyms APOLLO study

Most Recent Events

  • 17 Aug 2020 Status changed to completed, according to results published in the Clinical Cancer Research
  • 17 Aug 2020 Results published in the Clinical Cancer Research
  • 26 Sep 2018 Thirty-eight eligible patients were enrolled and 12 paired CSF-plasma samples were collected, according to results presented at the 19th World Conference on Lung Cancer.

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