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A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Study Evaluating the Efficacy and Safety of Guselkumab Administered Subcutaneously in Subjects With Active Psoriatic Arthritis

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Trial Profile

A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Study Evaluating the Efficacy and Safety of Guselkumab Administered Subcutaneously in Subjects With Active Psoriatic Arthritis

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 30 Jan 2024

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At a glance

  • Drugs Guselkumab (Primary)
  • Indications Psoriatic arthritis
  • Focus Registrational; Therapeutic Use
  • Acronyms DISC 2; Discover 2
  • Sponsors Janssen Research & Development; Janssen-Cilag
  • Most Recent Events

    • 01 Jan 2024 Results of post hoc analysis, assessing relationship between earlier clinical improvement and radiographic progression, published in the Clinical Rheumatology
    • 15 Nov 2023 Results of post hoc pooled analysis assessing PsA patients with substantial fatigue at baseline , relationships between early fatigue improvement and disease control at 1year, were presented at the ACR Convergence 2023.
    • 15 Nov 2023 Results of post hoc pooled analysis (n=473) assessing the impact on patient reported outcomes and individual entheseal points have differential frequency of involvement in patients with active psoriatic arthritis from DISCOVER-1 and DISCOVER-2 studies, presented at the ACR Convergence 2023.
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