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Discontinuation study of nilotinib in patients with chronic myeloid leukemia who have maintained complete molecular remission for at least 2 years: the prospective, multicenter stop study in Japan adult leukemia study group

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Discontinuation study of nilotinib in patients with chronic myeloid leukemia who have maintained complete molecular remission for at least 2 years: the prospective, multicenter stop study in Japan adult leukemia study group

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 30 Nov 2022

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At a glance

  • Drugs Nilotinib (Primary)
  • Indications Chronic myeloid leukaemia
  • Focus Therapeutic Use
  • Acronyms JALSG-N-STOP216

    • Most Recent Events

    • 29 Nov 2022 Planned End Date changed from 30 Jun 2021 to 30 Sep 2022.
    • 14 Dec 2021 Results assessing immune effects before and after TFR phase in two Japanese discontinuation trials of second-generation TKIs (JALSG N-STOP216 and D-STOP216), presented at the 63rd American Society of Hematology Annual Meeting and Exposition.
    • 17 Jun 2021 Results (n=51; data cut off date: December 14, 2020) assessing the rate of treatment-free remission at least 2 years on frontline nilotinib in patients with chronic myeloid leukemia in chronic phase, presented at the 26th Congress of the European Haematology Association.

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