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A 54-Week Treatment, Multicenter, Randomized, Double-Blind, Double-Dummy, Placebo and Active-Controlled, Parallel-Group Phase 2 Study to Assess the Efficacy and Safety of Brazikumab in Participants With Moderately to Severely Active Ulcerative Colitis

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Trial Profile

A 54-Week Treatment, Multicenter, Randomized, Double-Blind, Double-Dummy, Placebo and Active-Controlled, Parallel-Group Phase 2 Study to Assess the Efficacy and Safety of Brazikumab in Participants With Moderately to Severely Active Ulcerative Colitis

Status: Discontinued
Phase of Trial: Phase II

Latest Information Update: 11 Mar 2024

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At a glance

  • Drugs Brazikumab (Primary) ; Brazikumab (Primary) ; Vedolizumab
  • Indications Ulcerative colitis
  • Focus Therapeutic Use
  • Acronyms EXPEDITION
  • Sponsors AbbVie; Allergan; AstraZeneca
  • Most Recent Events

    • 03 Jul 2023 Planned End Date changed from 21 Jan 2025 to 13 Oct 2023.
    • 03 Jul 2023 Planned primary completion date changed from 14 Nov 2023 to 13 Oct 2023.
    • 01 Jun 2023 Status changed from recruiting to discontinued, according to a AstraZeneca media release.

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