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Effect of empagliflozin on the renin-angiotensin system in patients with chronic kidney disease with and without type 2 diabetes

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Trial Profile

Effect of empagliflozin on the renin-angiotensin system in patients with chronic kidney disease with and without type 2 diabetes

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 20 Apr 2022

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At a glance

  • Drugs Empagliflozin (Primary) ; Enalapril; Ramipril
  • Indications Renal failure
  • Focus Therapeutic Use
  • Acronyms EMPRA
  • Most Recent Events

    • 18 Apr 2022 Primary endpoint has not been met (The difference of Ang 1-7 increase from baseline between a 3-month treatment with empagliflozin on top of ACEi treatment compared to ACEi treatment alone), as per Results published in the Diabetes, Obesity and Metabolism
    • 18 Apr 2022 Results published in the Diabetes, Obesity and Metabolism
    • 12 Aug 2019 Status changed from recruiting to completed.
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