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A Phase 1, Dose-Escalation and Expansion Trial of PT2977, a HIF-2α Inhibitor, in Patients With Advanced Solid Tumors

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Trial Profile

A Phase 1, Dose-Escalation and Expansion Trial of PT2977, a HIF-2α Inhibitor, in Patients With Advanced Solid Tumors

Status: Active, no longer recruiting
Phase of Trial: Phase I/II

Latest Information Update: 01 Jul 2024

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At a glance

  • Drugs Belzutifan (Primary)
  • Indications Glioblastoma; Renal cell carcinoma; Solid tumours
  • Focus Adverse reactions; First in man
  • Acronyms LITESPARK-001
  • Sponsors Peloton Therapeutics
  • Most Recent Events

    • 04 Jun 2024 Results of glioblastoma expansion cohort (n=25) presented at the 60th Annual Meeting of the American Society of Clinical Oncology
    • 16 Sep 2022 Planned End Date changed from 14 Apr 2023 to 14 Apr 2025.
    • 07 Jun 2022 Results presented at the 58th Annual Meeting of the American Society of Clinical Oncology

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