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Single-Arm Phase II Trial of Dual Inhibition of EGFR With Afatinib and Cetuximab With Correlative Studies in the Treatment of Advanced Squamous Cell Cancers of the Head and Neck

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Trial Profile

Single-Arm Phase II Trial of Dual Inhibition of EGFR With Afatinib and Cetuximab With Correlative Studies in the Treatment of Advanced Squamous Cell Cancers of the Head and Neck

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 09 Feb 2026

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At a glance

  • Drugs Afatinib (Primary) ; Cetuximab (Primary)
  • Indications Head and neck cancer; Squamous cell cancer
  • Focus Therapeutic Use

Most Recent Events

  • 04 Feb 2026 Status changed from active, no longer recruiting to completed.
  • 07 May 2025 Planned End Date changed from 1 Dec 2027 to 1 Jan 2026.
  • 19 Mar 2025 Planned End Date changed from 1 Jan 2025 to 1 Dec 2027.

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